Dermigen - Dermigen Publications

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Dermigen Publications

Hanausek, M., Walaszek, Z., Viaje, A., LaBate, M., Spears, E., Farrell, D., Henrich, R., Tviet, A., Walborg, E.F., Jr., and Slaga, T.J., Exposure of mouse skin to organic peroxides: Subchronic effects related to carcinogenic potential. Carcinogenesis, 25: 431-437, 2004.
Chirase, N.K., Greene, L.W., Purdy, C.W., Loan, R.W., Auvermann, B.W., Parker, D.B., Walborg, E.F., Stevenson, D.E., Xu, Y., and Klaunig, J.E., The effect of transport stress on respiratory disease, serum antioxidant status and lipoperoxidation levels in beef attle. Am. J. Vet. Res., 65: 860-864, 2004.
Walborg, E.F., Jr., DiGiovanni, J., Topical Article. Role of Helicobacter pylori infection in the etiology of gastric cancer. Center for Research on Environmental Disease (CRED) Newsletter, October 2002.
Walborg, E.F., Jr., Comment on Donaldson v. Central Illinois Public Service Co., Forensic Panel Letter, February 15, 2001.
Kamendulis, L.M., Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Comparative effects of dieldrin on hepatic ploidy, cell proliferation and apoptosis in rodent liver. J. Toxicol. Environ. Health, 62: 127-141, 2001.
Stevenson, D.E. and Sielken, R.L., Jr., Are calories responsible for a decline in longevity? Hum. Exp. Toxicol., 19: 348-350, 2000.
Sielken, R.L., Jr., Bretzlaff, R.S., Valdez-Flores, C., Stevenson, D.E., and de Jong, G., Cancer dose-response modeling of epidemiological data on worker exposures to aldrin and dieldrin. Risk Analysis, 19: 1101-1111, 1999.
Stevenson, D.E., Walborg, E.F., Jr., North, D.W., Sielken, R.L., Jr., Ross, C.E., Wright, A.S., Xu, Y., Kamendulis, L.M., and Klaunig, J.E., Reassessment of human cancer risk of aldrin/dieldrin. Toxicol. Lett., 109: 123-186, 1999.
DiGiovanni, J., Johnston, D.A., Rupp, T., Sasser, L.B., Anderson, L.E., Morris, J.E., Miller, D.L., Kavet, R., and Walborg, E.F., Jr., Lack of effect of a 60 Hz magnetic field on biomarkers of tumor promotion in the skin of SENCAR mice. Carcinogenesis, 20: 685-689, 1999.
Walborg, E.F., Jr., DiGiovanni, J., Conti, C.J., Slaga, T.J., Freeman, J.J., Steup, D.R., and Skisak, C.M., Short-term biomarkers of tumor promotion in mouse skin treated with petroleum middle distillates. Toxicol. Sci., 45: 137-145, 1998.
Sasser, L.B., Anderson, L.E., Morris, J.E., Miller, D.L., Walborg, E.F., Jr., Kavet, R., Johnston, D.A., and DiGiovanni, J., Lack of a co-promoting effect of a 60 Hz magnetic field on skin tumorigenesis in SENCAR mice. Carcinogenesis, 19: 1617-1621, 1998.
Bachowski, S., Xu, Y., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Role of oxidative stress in the selective toxicity of dieldrin in the mouse liver. Toxicol. Appl. Pharmacol., 150: 301-309, 1998.
Sielken, R.L., Jr. and Stevenson, D.E., Some implications for quantitative risk assessment if hormesis exists. Human Exp. Toxicol., 17: 259-262. (reprinted from Belle Newsletter, 6: 13-17, 1998).
Sielken, R.L. and Stevenson, D.E., Modeling to incorporate defense mechanisms into the estimation of dose-responses. Environ. Health Persp., 106: 341-348, 1998.
Klaunig, J.E., Xu, Y., Isenberg, J.S., Bachowski, S., Kolaja, K.L., Jiang, J., Stevenson, D.E., and Walborg, E.F., Jr., The role of oxidative stress in chemical carcinogenesis. Environ. Health Persp., 106: 289-295, 1998.
Kolaja, K.L., Walborg, E.F., Jr., Stevenson, D.E., and Klaunig, J.E., Vitamin E modulation of dieldrin-induced hepatic focal lesion growth in mice. J. Toxicol. Environ. Health, Part A, 53: 479-492, 1998.
Sielken, R.L. and Stevenson, D.E., Some implications for quantitative risk assessment if hormesis exists. Belle Newsletter, 6: 13-17, 1998.
Sielken, R.L., Bretzlaff, R.S., Stevenson, D.E., and deJong, G., Updated mortality analyses of Pernis epidemiological data on human exposures to aldrin and dieldrin. Human and Ecological Risk Assessment, 4: 201-225, 1998.
DiGiovanni, J., Johnston, D.A., Walborg, E.F., Jr., Anderson, L.E., Sasser, L.B., Morris, J.E., Miller, D.L., and Kavet, R., Evaluation of the Possible Co-promoting Effect of a 60 Hz Magnetic Field During Chemically Induced Carcinogenesis in Skin of SENCAR Mice, EPRI TR-109471 Final Report, Electric Power Research Institute, November, 1997.
Sielken, R.L. and Stevenson, D.E., Opportunities to improve quantitative risk assessment. Human and Ecological Risk Assessment, 3: 479-489, 1997.
Bachowski, S., Kolaja, K.L., Xu, Y., Ketcham, C.A., Stevenson, D.E., Walborg, E.F., Jr., Klaunig, J.E., Role of oxidative stress in the mechanism of dieldrin’s hepatotoxicity. Ann. Clin. Lab. Science, 27: 196-209, 1997.
Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Reversibility of promoter induced hepatic focal lesion growth in mice. Carcinogenesis, 17: 1403-1409, 1996.
Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Selective dieldrin promotion of hepatic focal lesions in mice. Carcinogenesis, 17: 1243-1250, 1996.
Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Dose-dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: Effects on DNA synthesis and apoptosis. Carcinogenesis, 17: 947-954, 1996.
Marshall, M.V., Kuhn, J.O., Torrey, C.F., Fischman, S.L., and Cancro, L.P. Hamster cheek pouch bioassay of dentifrices containing hydrogen peroxide and baking soda. J. Am. Coll. Toxicol., 15: 45-61, 1996.
Kolaja, K.L., Stevenson, D.E., Johnson, J.T., Walborg, E.F., Jr., and Klaunig, J.E. Subchronic effects of dieldrin and phenobarbital on hepatic DNA synthesis in mice and rats. Fund. Appl. Toxicol., 29: 219-228, 1996.
Klaunig, J.E., Xu, Y., Bachowski, S., Ketcham, C.A., Isenberg, J.S., Kolaja, K.L., Baker, T.K., Walborg, E.F., Jr., Stevenson, D.E. Oxidative stress in nongenotoxic carcinogenesis. Toxicol. Lett., 82/83: 683-691, 1995.
Lu, L-J.W., Broemeling, L.D., Marshall, M.V., and Ramanujam, V.M.S. A simplified method to quantify isoflavones in commercial soybean diets and human urine after legume consumption. Cancer Epidemiol. Biomark. and Prevent., 4: 497-503, 1995.
Marshall, M.V., Cancro, L.P., and Fischman, S.L. Hydrogen peroxide: A review of the use in dentistry. J. Periodontol., 66: 786-796, 1995.

Stevenson, D.E. and Sielken, R.L, Jr. The low-dose response in cancer studies may not be linear. In: Proceedings of the 1995 Annual Summer Meeting of the Toxicology Forum, held July 10-14, 1995 in Aspen, Colorado, The Toxicology Forum, Washington, D.C., pp. 671-680, 1995.
Bachowski, S, Xu, Y., Baker, T. K., Stevenson, D. E., Walborg, E. F., Jr., and Klaunig, J. E. The potential role of oxidative stress in nongenotoxic carcinogenesis in the mouse liver. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, pp. 385-396. New York: Wiley-Liss, 1995.
Baker, T. K., Bachowski, S., Stevenson, D. E., Walborg, E. F., Jr., and Klaunig, J. E., Modulation of gap junctional intercellular communication in rodent, monkey and human hepatocyte by nongenotoxic compounds. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, pp. 71-80. New York: Wiley-Liss, 1995.
Kolaja, K. L., Stevenson, D. E., Johnson, J. T., Walborg, E. F., Jr., and Klaunig, J. E. Hepatic effects of dieldrin and phenobarbital in male B6C3F1 mice and Fisher 344 rats: Species selective induction of DNA synthesis. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, pp. 397-408. New York: Wiley-Liss, 1995.
Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E. The Effect of dieldrin and phenobarbital on preneoplastic hepatic lesion growth in male F344 rat and B6C3F1 mouse. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, pp. 409-423. New York: Wiley-Liss, 1995.
Stevenson, D. E., Walborg, E. F., Jr., and Klaunig, J. E. The species specificity of dieldrin- or phenobarbital-induced hepatocarcinogenesis: Case studies with implications for human risk assessment. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, pp. 337-345. New York: Wiley-Liss, 1995.
Skisak, C., DiGiovanni, J., Conti, C. J., Slaga, T. J., Sharma, S., Sagartz, J. W., and Walborg, E. F., Jr. Induction of short-term biomarkers of tumor promotion in skin of CD-1 mice by petroleum middle distillates: Preliminary observations. In: M. McClain, T. J. Slaga, R. A. LeBoeuf, and H. Pitot (eds.), Growth Factors and Tumor Promotion: Implications for Risk Assessment, New York: Wiley-Liss, 1995.
Marshall, M.V., Carey, K.D., Von Hoff, D.D., and Kuhn, J.G. Hepsulfam distribution in blood, plasma and cerebrospinal fluid of baboons. Invest. New Drugs, 13: 33-36, 1995.
Sielken, R. L., Jr., Bretzlaff, R. S., and Stevenson, D. E. Challenges to default assumptions stimulate comprehensive realism as a new tier in quantitative cancer risk assessment. Reg. Toxicol. Pharmacol., 21: 270-280,1995.
Stevenson, D. E. Dose-response studies of genotoxic rodent carcinogens: Thresholds, hockey sticks, hormesis, or straight lines? Belle Newsletter, 3: 14-15, 1995.

Stevenson, D. E., Kehrer, J. P., Kolaja, K. L., Walborg, E. F., Jr., and Klaunig, J. E. Effect of dietary antioxidants on dieldrin-induced hepatotoxicity in mice, Toxicol. Lett., 75: 177-183, 1995.

Sielken, R. L., Jr. and Stevenson, D. E. Another flaw in the linearized multistage model upper bounds on human cancer potency. Reg. Toxicol. Pharmacol., 19: 106-114, 1994.
Stevenson, D. E. Case studies illustrating the type of data needed for departure from classic default assumptions: Species specificity of dieldrin and phenobarbital in heptotoxicity. In: Proceedings of the 1994 Annual Summer Meeting of the Toxicology Forum, held July 11-15, 1994 in Aspen, Colorado, The Toxicology Forum, Washington, D.C., 1994.
Stevenson, D. E., Bretzlaff, R. S., Sielken, R. L., Jr., and MacDonald, R. L. Dose-response characterization of life, death, and hormesis. Comments on Toxicol., 5: 151-180, 1994.
Stevenson, D E., Sielken, R. L., Jr., and Bretzlaff, R. S. Challenges to low-dose linearity in carcinogenesis from interactions among mechanistic components as exemplified by the concept of “invaders” and “defenders.” Belle Newsletter 3: 1-8, 1994.
Walborg, E. F., Jr. Extremely low frequency electromagnetic fields and cancer: Focus on tumor initiation, promotion, and progression. National Electrical Manufacturers Association, Washington, D.C., 125 pages, 1991.

Hanausek, M., Walaszek, Z., Viaje, A., LaBate, M., Spears, E., Farrell, D., Henrich, R., Tviet, A., Walborg, E.F., Jr., and Slaga, T.J., Exposure of mouse skin to organic peroxides: Subchronic effects related to carcinogenic potential. Carcinogenesis, 25: 431-437, 2004.

Walborg, E.F., Jr., DiGiovanni, J., Topical Article. Role of Helicobacter pylori infection in the etiology of gastric cancer. Center for Research on Environmental Disease (CRED) Newsletter, October 2002.

Walborg, E.F., Jr., Comment on Donaldson v. Central Illinois Public Service Co., Forensic Panel Letter, February 15, 2001.

Kamendulis, L.M., Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Comparative effects of dieldrin on hepatic ploidy, cell proliferation and apoptosis in rodent liver. J. Toxicol. Environ. Health, 62: 127-141, 2001.

Stevenson, D.E. and Sielken, R.L., Jr., Are calories responsible for a decline in longevity? Hum. Exp. Toxicol., 19: 348-350, 2000.

Sielken, R.L., Jr., Bretzlaff, R.S., Valdez-Flores, C., Stevenson, D.E., and de Jong, G., Cancer dose-response modeling of epidemiological data on worker exposures to aldrin and dieldrin. Risk Analysis, 19: 1101-1111, 1999.

Stevenson, D.E., Walborg, E.F., Jr., North, D.W., Sielken, R.L., Jr., Ross, C.E., Wright, A.S., Xu, Y., Kamendulis, L.M., and Klaunig, J.E., Reassessment of human cancer risk of aldrin/dieldrin. Toxicol. Lett., 109: 123-186, 1999.

DiGiovanni, J., Johnston, D.A., Rupp, T., Sasser, L.B., Anderson, L.E., Morris, J.E., Miller, D.L., Kavet, R., and Walborg, E.F., Jr., Lack of effect of a 60 Hz magnetic field on biomarkers of tumor promotion in the skin of SENCAR mice. Carcinogenesis, 20: 685-689, 1999.

Walborg, E.F., Jr., DiGiovanni, J., Conti, C.J., Slaga, T.J., Freeman, J.J., Steup, D.R., and Skisak, C.M., Short-term biomarkers of tumor promotion in mouse skin treated with petroleum middle distillates. Toxicol. Sci., 45: 137-145, 1998.

Sasser, L.B., Anderson, L.E., Morris, J.E., Miller, D.L., Walborg, E.F., Jr., Kavet, R., Johnston, D.A., and DiGiovanni, J., Lack of a co-promoting effect of a 60 Hz magnetic field on skin tumorigenesis in SENCAR mice. Carcinogenesis, 19: 1617-1621, 1998.

Bachowski, S., Xu, Y., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Role of oxidative stress in the selective toxicity of dieldrin in the mouse liver. Toxicol. Appl. Pharmacol., 150: 301-309, 1998.

Sielken, R.L., Jr. and Stevenson, D.E., Some implications for quantitative risk assessment if hormesis exists. Human Exp. Toxicol., 17: 259-262. (reprinted from Belle Newsletter, 6: 13-17, 1998).

Sielken, R.L. and Stevenson, D.E., Modeling to incorporate defense mechanisms into the estimation of dose-responses. Environ. Health Persp., 106: 341-348, 1998.

Klaunig, J.E., Xu, Y., Isenberg, J.S., Bachowski, S., Kolaja, K.L., Jiang, J., Stevenson, D.E., and Walborg, E.F., Jr., The role of oxidative stress in chemical carcinogenesis. Environ. Health Persp., 106: 289-295, 1998.

Kolaja, K.L., Walborg, E.F., Jr., Stevenson, D.E., and Klaunig, J.E., Vitamin E modulation of dieldrin-induced hepatic focal lesion growth in mice. J. Toxicol. Environ. Health, Part A, 53: 479-492, 1998.

Sielken, R.L. and Stevenson, D.E., Some implications for quantitative risk assessment if hormesis exists. Belle Newsletter, 6: 13-17, 1998.

Sielken, R.L., Bretzlaff, R.S., Stevenson, D.E., and deJong, G., Updated mortality analyses of Pernis epidemiological data on human exposures to aldrin and dieldrin. Human and Ecological Risk Assessment, 4: 201-225, 1998.

Sielken, R.L. and Stevenson, D.E., Opportunities to improve quantitative risk assessment. Human and Ecological Risk Assessment, 3: 479-489, 1997.

Bachowski, S., Kolaja, K.L., Xu, Y., Ketcham, C.A., Stevenson, D.E., Walborg, E.F., Jr., Klaunig, J.E., Role of oxidative stress in the mechanism of dieldrin’s hepatotoxicity. Ann. Clin. Lab. Science, 27: 196-209, 1997.

Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Reversibility of promoter induced hepatic focal lesion growth in mice. Carcinogenesis, 17: 1403-1409, 1996.

Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Selective dieldrin promotion of hepatic focal lesions in mice. Carcinogenesis, 17: 1243-1250, 1996.

Kolaja, K.L., Stevenson, D.E., Walborg, E.F., Jr., and Klaunig, J.E., Dose-dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: Effects on DNA synthesis and apoptosis. Carcinogenesis, 17: 947-954, 1996.

Marshall, M.V., Kuhn, J.O., Torrey, C.F., Fischman, S.L., and Cancro, L.P. Hamster cheek pouch bioassay of dentifrices containing hydrogen peroxide and baking soda. J. Am. Coll. Toxicol., 15: 45-61, 1996.

Kolaja, K.L., Stevenson, D.E., Johnson, J.T., Walborg, E.F., Jr., and Klaunig, J.E. Subchronic effects of dieldrin and phenobarbital on hepatic DNA synthesis in mice and rats. Fund. Appl. Toxicol., 29: 219-228, 1996.

Klaunig, J.E., Xu, Y., Bachowski, S., Ketcham, C.A., Isenberg, J.S., Kolaja, K.L., Baker, T.K., Walborg, E.F., Jr., Stevenson, D.E. Oxidative stress in nongenotoxic carcinogenesis. Toxicol. Lett., 82/83: 683-691, 1995.

Lu, L-J.W., Broemeling, L.D., Marshall, M.V., and Ramanujam, V.M.S. A simplified method to quantify isoflavones in commercial soybean diets and human urine after legume consumption. Cancer Epidemiol. Biomark. and Prevent., 4: 497-503, 1995.

Marshall, M.V., Cancro, L.P., and Fischman, S.L. Hydrogen peroxide: A review of the use in dentistry. J. Periodontol., 66: 786-796, 1995.

Stevenson, D.E. and Sielken, R.L, Jr. The low-dose response in cancer studies may not be linear. In: Proceedings of the 1995 Annual Summer Meeting of the Toxicology Forum, held July 10-14, 1995 in Aspen, Colorado, The Toxicology Forum, Washington, D.C., pp. 671-680, 1995.

Marshall, M.V., Carey, K.D., Von Hoff, D.D., and Kuhn, J.G. Hepsulfam distribution in blood, plasma and cerebrospinal fluid of baboons. Invest. New Drugs, 13: 33-36, 1995.

Sielken, R. L., Jr., Bretzlaff, R. S., and Stevenson, D. E. Challenges to default assumptions stimulate comprehensive realism as a new tier in quantitative cancer risk assessment. Reg. Toxicol. Pharmacol., 21: 270-280,1995.

Stevenson, D. E. Dose-response studies of genotoxic rodent carcinogens: Thresholds, hockey sticks, hormesis, or straight lines? Belle Newsletter, 3: 14-15, 1995.

Stevenson, D. E., Kehrer, J. P., Kolaja, K. L., Walborg, E. F., Jr., and Klaunig, J. E. Effect of dietary antioxidants on dieldrin-induced hepatotoxicity in mice, Toxicol. Lett., 75: 177-183, 1995.

Sielken, R. L., Jr. and Stevenson, D. E. Another flaw in the linearized multistage model upper bounds on human cancer potency. Reg. Toxicol. Pharmacol., 19: 106-114, 1994.

Stevenson, D. E., Bretzlaff, R. S., Sielken, R. L., Jr., and MacDonald, R. L. Dose-response characterization of life, death, and hormesis. Comments on Toxicol., 5: 151-180, 1994.

Stevenson, D E., Sielken, R. L., Jr., and Bretzlaff, R. S. Challenges to low-dose linearity in carcinogenesis from interactions among mechanistic components as exemplified by the concept of “invaders” and “defenders.” Belle Newsletter 3: 1-8, 1994.

Walborg, E. F., Jr. Extremely low frequency electromagnetic fields and cancer: Focus on tumor initiation, promotion, and progression. National Electrical Manufacturers Association, Washington, D.C., 125 pages, 1991.